Visual quality observation of transepithelial photorefractive keratectomy and femtosecond small incision lenticule extraction for the correction of low myopia / 国际眼科杂志(Guoji Yanke Zazhi)

AIM:To observe the changes in corneal aberrations and the characteristics of visual quality after transepithelial photorefractive keratectomy(T-PRK)and femtosecond small incision lenticule extraction(SMILE)in the correction of low myopia.METHODS: Prospective cohort study. A total of 32 cases(32 eyes)with low myopia who underwent T-PRK surgery and 45 cases(45 eyes)of SMILE surgery at Weifang Eye Hospital from April 2021 to April 2022 were selected. The uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), spherical equivalent(SE), corneal higher-order aberrations(HOAs)and objective visual quality were compared between the two groups.RESULTS:All patients completed the surgery successfully without complications such as infection. At 3mo postoperatively, the safety index was 1.13±0.16 and 1.16±0.17(P=0.48)and the efficacy index was 1.10±0.20 and 1.15±0.18(P=0.27)in the T-PRK and SMILE groups, respectively. The percentage of UCVA(LogMAR)≤0 in the T-PRK and SMILE groups was 94% and 98%, respectively. The percentage of the residual SE within ±0.5D was 88% and 87% in the two groups, respectively. The HOAs and spherical aberration in both groups were significantly increased(P≤0.01), and the increase was not statistically significant between the two groups(P=0.31, 0.89). There was no significant change in horizontal coma, horizontal trefoil and vertical trefoil in both groups(P>0.05). The vertical coma in SMILE group was significantly increased(P<0.001), while there was no significant change in T-PRK group(P>0.05), and the increase was significantly greater in SMILE group than in T-PRK group(P<0.001). There was no significant difference in objective scattering index(OSI), modulation transfer function cut off frequency(MTFcut off), Strehl ratio(SR), visual acuity(VA)100%, VA20% and VA9% between the two groups(P>0.05).CONCLUSION:Both T-PRK and SMILE showed good safety, efficacy, and visual quality in correcting low myopia, while SMILE induced more vertical coma than T-PRK.

Short-term visual quality observation of femtosecond laser small incision lenticule extraction and evolution implantable collamer lens implantation in the correction of moderate myopia / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: To investigate the short-term visual quality outcomes after femtosecond laser small incision lenticule extraction(SMILE)and evolution implantable collamer lens(EVO-ICL)implantation for the correction of moderate myopia.METHODS: Prospective control study. A total of 51 cases(51 eyes)with moderate myopia who underwent SMILE or EVO-ICL implantation surgery at Weifang Eye Hospital from April 2021 to February 2022 were selected. They were divided into SMILE group(30 patients, 30 eyes)and EVO-ICL group(21 patients, 21 eyes)according to the surgical methods. The changes of visual acuity [uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA)], diopter [spherical equivalent(SE)] and related parameters of optical quality analysis system(OQAS Ⅱ)were observed before surgery and at 1wk, 1 and 3mo after surgery, and the quality of vision(QoV)questionnaire was completed.RESULTS: At 3mo after surgery, the safety index(postoperative CDVA/preoperative CDVA)of SMILE gruop and EVO-ICL group were 1.20(1.00, 1.20)and 1.20(1.00, 1.38), respectively, the efficacy index(postoperative UDVA/preoperative CDVA)were 1.00(1.00, 1.20)and 1.00(1.00, 1.20), respectively, and the percentage of SE within ±0.50D was 87% and 100%, respectively. In SMILE group, the objective scattering index(OSI)was increased after surgery, while modulation transfer function cutoff frequency(MTF cutoff), contrast visual acuity(VA)100%, and VA20% at 1wk and 1mo after surgery, and Strehl ratio(SR)and VA9% at each time point after surgery were all decreased compared with those before surgery(all P<0.05). The OSI, MTF cutoff, SR and VA of EVO-ICL group showed no difference at each time point after surgery compared with those before surgery(all P>0.05). The most common visual symptoms after SMILE and EVO-ICL implantation were visual haze and halos, respectively.CONCLUSION: Both SMILE and EVO-ICL implantation have good safety, efficacy and predictability in the short term after the correction of moderate myopia. Both groups had visual symptoms after surgery, but the overall satisfaction of patients was high. Furthermore, EVO-ICL implantation has better objective visual quality performance.

Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children

Purpose: The present study was performed to compare the optical quality of the eyes of myopic children before and after treatment with atropine eye drops of different concentrations. Methods: In the study population of 71 patients (131 eyes), 34 patients (63 eyes) were given 0.01% atropine eye drops and 37 patients (68 eyes) were given 0.05% atropine eye drops. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs 100%, 20%, and 9%) under different lighting conditions were measured before and after two weeks of atropine treatment. Results: After using 0.05% atropine eye drops for two weeks, the Strehl ratio decreased from 0.27 ± 0.07 to 0.23 ± 0.07 (P = 0.0026), PVA 20% decreased from 1.15 ± 0.32 to 1.03 ± 0.36 (P = 0.0344), and PVA 9% decreased from 0.74 ± 0.23 to 0.64 ± 0.23 (P = 0.0073). The OSI was significantly higher after using 0.05% than 0.01% atropine eye drops (P = 0.0396), while both the Strehl ratio and PVA 20% were lower after using 0.05% than 0.01% atropine eye drops (P = 0.0087 and P = 0.0492, respectively). Conclusion: The children’s optical quality did not change significantly after using 0.01% atropine eye drops, whereas it decreased after using 0.05% atropine eye drops.

Optical quality assessment in patients with macular edema using optical quality analysis system / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM:To evaluate optical quality, intraocular scatter, and determine the impact of retinopathy on optical quality in macular edema(ME)patient by using the Optical Quality Analysis System(OQAS^TMⅡ).<p>METHODS: This was a prospective case-control study. Fifty-eight eyes of 49 macular edema patients who were confirmed by ophthalmic examination in our hospital from August 2019 to January 2020 were selected as the ME group, and 30 eyes of 30 healthy volunteers who were matched with gender and age range for the study were selected for the normal control group. The clinical data of the two groups of patients were recorded. Under the same test conditions, the same operator used OQAS^TMⅡ to check the visual quality of the study object, including the cutoff of the modulation transfer function(MTF cutoff), strehl ratio(SR), OQAS^TMⅡ values(100%, 20%, 9%)and contrast levels(OV100%, OV20%, OV9%). The difference of data between the two groups were analyzed, and the correlation between the visual quality and the thickness and volume of the macular fovea in the ME group were analyzed.<p>RESULTS: The average best corrected visual acuity in the macular edema group was significantly lower than the control group, and the thickness and volume of macular fovea were significantly higher than the control group(<i>P</i><0.001). Compared with the control group, the OSI of the macular edema group was significantly higher, and MTF cutoff, SR value, OV(100%, 20%, 9%)significantly decreased(<i>P</i><0.001). In the macular disease group, the thickness of macular fovea was positively correlated with OSI(<i>r</i>=0.566, <i>P</i><0.001), while MTF cutoff(<i>r</i>=-0.336, <i>P</i>=0.010), OV100%(<i>r</i>=-0.326, <i>P</i>=0.013), OV20%(<i>r</i>=-0.349, <i>P</i>=0.007)and OV9%(<i>r</i>=-0.321, <i>P</i>=0.014)were negative correlation, but it had no correlation with SR. In the macular edema group, the volume of macular fovea was positively correlated with OSI(<i>r</i>=0.574, <i>P</i><0.001). It was negatively correlated with MTF cutoff(<i>r</i>=-0.367, <i>P</i>=0.005), SR(<i>r</i>=-0.265, <i>P</i>=0.045), OV100%(<i>r</i>=-0.351, <i>P</i>=0.007), OV20%(<i>r</i>=-0.385, <i>P</i>=0.003)and OV9%(<i>r</i>=-0.375, <i>P</i>=0.004).<p>CONCLUSION: The optical quality of patients with macular edema is lower than the normal population, and the changes in macular retina morphology and thickness could affect the optical quality and intraocular scattering. The optical quality parameters measured by OQAS^TMⅡ may provide new clinical reference for macular function evaluation.

Prediction on postoperative visual acuity of cataract patients by objective quality analysis system / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To assess the accuracy of optical quality analysis system Ⅱ(OQAS Ⅱ)in predicting postoperative visual acuity of cataract patients.<p>METHODS: Prospective study, patients underwent cataract surgery in Daping Hospital from June 2019 to November 2019 were recruited. According to predicted visual acuity 100%(PVA100%)and best corrected visual acuity(BCVA), patients were dichotomized into group A(PVA100% worse than BCVA, 145 eyes)and group B(PVA100% equal to or better than BCVA, 114 eyes). Visual acuity improvement was compared between the two groups 1mo after surgery.<p>RESULTS: In group A, visual acuity of 112 eyes(77.2%)improved at least 2 lines. While in group B, 93 eyes(81.6%)improved at least 2 lines. There was no significant difference in visual acuity improvement ratio between the two groups(<i>P</i>=0.394). The average BCVA improvement of group A was 0.3(0.2, 0.4)LogMAR, and that of group B was 0.4(0.2, 0.5)LogMAR, revealed statistically significant differences(<i>P</i>=0.001). No significant correlation was found between preoperative PVA100% and postoperative BCVA in both of the two groups(<i>P</i>=0.888,0.304). In patients combined with preoperative ocular comorbidity, 17 eyes(94.4%)in group A and 26 eyes(65.0%)in group B improved at least 2 lines with significant difference between the two groups(<i>P</i>=0.041). BCVA improved 0.3(0.2, 0.4)LogMAR in group A and 0.3(0.1, 0.5)LogMAR in group B, there was no significant difference between the two groups(<i>P</i>=0.597).<p>CONCLUSION: The binary classification method based on the value of preoperative PVA100% and BCVA failed to accurately predict who shall benefit more from cataract surgery. In patients diagnosed with preoperative ocular comorbidity, BCVA is likely to be significantly improved if preoperative PVA100% were worse than BCVA. More data are needed to determine the clinical value of PVA100%.

Analysis of short-term objective visual quality after two kinds of corneal refractive surgery / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To analyze changes in objective visual quality before and after femtosecond laser <i>in situ</i> keratomileusis(FS-LASIK)and smart pulse technology-assisted transepithelial photorefractive keratectomy(SMART).<p>METHODS: Prospective study. We collected 50 cases(100 eyes)treated with FS-LASIK(FS-LASIK group)and another 50 cases(100 eyes)treated with SMART(SMART group)from the Ophthalmology Department of our hospital between October 2018 and December 2018 using Optical Quality Analysis System(OQAS)to measure objective scatter index(OSI), modulation transfer function cut off frequency(MTF cut off), strehl ratio(SR)before and after surgery.<p>RESULTS: In the FS-LASIK and SMART groups, the OSI values were higher in the 1 and 3mo after surgery, whereas the MTF cut off and SR were lower in the 1 and 3mo after surgery(<i>P</i><0.05). There was no statistical difference between the two groups in the objective visual quality index before and after 1mo(<i>P</i>>0.05). However, after 3mo, the OSI value of the FS-LASIK group was higher than the SMART group(0.88±0.28 <i>vs</i> 0.70±0.27, <i>P</i><0.001), whereas the SR was lower than SMART group(0.21±0.05 <i>vs</i> 0.24±0.05, <i>P</i>=0.002).<p>CONCLUSION: Both FS-LASIK and SMART caused an increase in the intraocular scattering index and a decrease in objective visual quality. However, the visual quality of the SMART group was generally better than that of the FS-LASIK group, and long-term visual quality was more dominant.

Comparison of early postoperative effects between SMART and TransPRK / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To evaluate the early postoperative efficacy of SMART for myopia and compare it with TransPRK.<p>METHODS: Retrospective non-randomized controlled study. Totally 120 eyes of 60 patients with myopia who underwent SMART and TransPRK in our hospital from January to August 2018 were selected respectively. The uncorrected visual acuity(UCVA), visual quality, pain score, corneal epithelial healing and subepithelial haze were compared between two groups.<p>RESULTS: There was no statistical differences between two groups regarding the proportion of UCVA reaching or exceeding 1.0 at 5d, 1mo and 3mo after operation(<i>P</i>>0.05), but the visual quality of SMART group was better than that of TransPRK group at 5d after operation(<i>P</i><0.05), and with the prolongation of time, the visual quality of the two groups gradually improved. There was a significant difference in pain scores between the TransPRK group and SMART group(3.56±0.96 <i>vs</i> 3.07±1.07; 1.22±0.61 <i>vs</i> 0.84±0.59)on the 1st day and 3rd day after operation(<i>P</i><0.01). 5d after operation, the complete recovery rate of corneal in TransPRK group was lower than that in SMART group(69.2% <i>vs</i> 83.3%, <i>P</i><0.05). At 1st and 3 mo after operation, there was no difference in haze between the two groups(5.0% <i>vs</i> 5.0% and 8.3% <i>vs</i> 10.0%; <i>P</i>>0.05).<p>CONCLUSION: There is no significant difference between SMART and TransPRK in the speed and stability of visual acuity recovery, but the early postoperative pain of SMART is lighter, the corneal epithelium is healed faster, and the visual quality is better.

Accuracy of qualitative prediction in cataract surgery by double-pass optical quality analysis system / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To evaluate the accuracy of qualitative prediction of cataract surgery by double-pass optical quality analysis system(OQASTMⅡ).<p>METHODS: A retrospective study was conducted. Totally 57 cataract patients(67 eyes)were randomly selected from October 2018 to December 2018 in Renmin Hospital of Wuhan University. According to the objective scattering index(OSI), they were divided into group A(28 eyes, OSI>8.0), group B(28 eyes, OSI≤8.0), and group C(11 eyes, OSI could not be detected due to severe lens opacity). The effect of surgery was predicted by Predicted VA100% and preoperative BCVA.<p>RESULTS: In group A, 26 eyes(93%)comply with the standard, and in group B, 24 eyes(86%)comply with the standard. There was no significant difference between the two groups(<i>P</i>=0.669). Besides, no correlation was found between Predicted VA100% and postoperative 2wk BCVA(<i>r</i>_s=0.103, <i>P</i>>0.5).<p>CONCLUSION: The OQASTMⅡ system can objectively, accurately and intuitively predict the effect of cataract surgery.

Effect of posterior chamber introcular lens implantation on high myopia / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To evaluate the clinical efficacy of the posterior chamber intraocular lens(ICL)implantation for high myopia by the double-pass optical quality analysis system II(OQAS II).<p>METHODS: A total of 26 eyes of 52 patients with high myopia admitted to the First Affiliated Hospital of Anhui Medical University from December 2017 to December 2018 were selected. All patients underwent ICL implantation. Follow-up to obtain the best corrected visual acuity(BCVA)of all patients. And a series of parameters, such as uncorrected visual acuity(UCVA), object scatter index(OSI), modulation transfer function(MTF), Strehl ratio(SR)and Predicted VA of 100%,20% and 9%,were obtained before and 1wk,1 and 3mo after operation.<p>RESULTS: Compared with preoperative UCVA and BCVA, the 1wk, 1 and 3mo UCVA were better than preoperative and gradually improved, and the differences were statistically significant(<i>P</i><0.01). Compared with OSI, MTF, SR and Predicted VA 100%, 20% and 9% before operation, the situation improved at 1wk,1 and 3mo after operation, with statistical significance(<i>P</i><0.01).<p>CONCLUSION: ICL implantation can effectively correct high myopia and improve UCVA. Through OQAS II analysis, OSI was reduced after ICL implantation. The postoperative MTF, SR and Predicted VA of 100%, 20% and 9% higher than those before surgery. The visual quality of patients with high myopia was improved after ICL implantation.

Evaluation of visual quality in eyes implanted with different types of multifocal intraocular lenses by optical quality analysis system / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To measure the optical quality after implantation of SBL-3 and SN6AD1 multifocal intraocular lens(MIOL)in patients by a double-pass optical quality analysis system(OQAS).<p>METHODS: Totally 47 cases of age-related cataract who received phacoemulsification and the implantation of MIOL were enrolled from March 2017 to April 2018 in Chengdu Aier Eye Hospital. According to the difference of implanted MIOLs, patients were divided into SBL-3 group(22 patients, 22 eyes)and SN6AD1 group(25 patients, 25 eyes). Three months postoperatively, uncorrected distant visual acuity(UDVA), uncorrected intermediate visual acuity(UIVA), uncorrected near visual acuity(UNVA), corrected distant visual acuity(CDVA), corrected intermediate visual acuity(CIVA), corrected near visual acuity(CNVA), and objective optical quality measured by OQAS were all compared between two groups.<p>RESULTS: Three months postoperatively, significant difference was found in UIVA \〖0.14(0.04, 0.26)<i>vs</i> 0.26(0.12, 0.40), <i>P</i><0.05\〗 which was better in SBL-3 group. Moreover, significantly higher values of OSI \〖2.52(2.35, 3.86)<i>vs</i> 1.89(1.39, 2.28)\〗 and pseudophakic accommodation(2.47±0.88D <i>vs</i> 1.25±0.70D)were found in SBL-3 group. Significantly lower values of MTF-cut/off, SR, OV 100%, OV 20% and OV 9% were found in SBL-3 group(<i>P</i><0.01).<p>CONCLUSION: Both SBL-3 and SN6AD1 MIOL could provide patients with good subjective visual quality, but OQAS could find the differences in visual quality after implantation of different MIOLs objectively.

Analysis of visual quality after posterior chamber ICL implantation and FS-LASIK / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To compare the visual quality between implantable collamer lens(ICL)implantation and FS-LASIK for correcting moderate and high myopia.<p>METHODS: Prospective study. Choose in June 2018 to December 2018 for ICL implantation of 58 patients(116 eyes)and 48 patients(96 eyes)underwent FS-LASIK. The diopter, visual acuity and visual quality of the two groups before and after surgery were analyzed and compared.<p>RESULTS: After 3mo operation, the degree of spherical mirror in the ICL group was higher than that in the FS-LASIK group(0.19±0.22D <i>vs</i> 0.09±0.29D, <i>P</i><0.05), but there was no difference in visual acuity, lenticule degree and spherical equivalent between the two groups(<i>P</i>>0.05). The modulation transfer function cut off frequency(MTF cut off), objective scatter index(OSI)and OV9% were significantly better in the ICL group than in the FS-LASIK group, while the SR was lower than the FS-LASIK group. Compared with the former, the MTF cut off was significantly increased in the ICL group, the SR and OSI values were decreased, and the SR value was decreased in the FS-LASIK group(all <i>P</i><0.05).<p>CONCLUSION: Both ICL implantation and FS-LASIK can effectively improve the visual acuity and diopter of patients, ICL implantation for patients with moderate and high myopia provides relatively good visual quality.<p>

An evaluation on visual quality for patients with high myopia complicated with cataract post intraocular lens implantation by using double-pass optical quality analysis system / 中国医学装备

Objective: To analyze and explore the application of duable-pass optical quality analysis system(OQAS) on the evaluation of visual quality for patients with high myopia complicated with cataract who received intraocular lens implantation. Methods: The documents of 93 patients with high myopia complicated with cataract were collected in the retrospective analysis. And all of patients received ultrasonic emulsification and intraocular lens implantation. And then the visual situation and the changes of PSF, OSI, MTF, MTFcutoff, SR, OV100%, OV20%and OV9%were evaluated by using double-pass OQAS at three points included pre-operation, 1week of post-operation and 1month of post-operation. Results: After treatment, the visual situation of patients were significantly improved, and the differences of visual situations among pre-operation, 1 week of post-operation and 1 month of post operation were significant (F=6.831, P<0.05). And the differences of OSI, PSF and OV9%between the before and after treatment were significant (F=6.732, F=9.102, F=5.029, P<0.05), respectively. While the differences of MTFcutoff, SR, OV100%and OV20% between the two groups were no significant. Under the conditions of 5 cpd and 10 cpd of MTF, the differences of MTF among pre-operation, 1 week post operation and 1month post operation were significant (F=8.029, F=4.039, P<0.05), respectively. Besides, at 1 week post-operation and 1month post-operation, the differences among 5cpd, 10cpd and 15cpd were significant(F=7.829, F=6.921, P<0.05), respectively. Conclusion: After the patients with high myopia complicated with cataract receive intraocular lens implantation of ultrasonic emulsification, the visual analysis system of dual channel can preferably evaluate the visual quality of patients, and can objectively reflect aberration, scattering and diffraction, etc. Therefore, it is worthy to be popularized and applied.

Comparison of patients' vision and visual quality following refractive rotationally asymmetric mutifocal intraocular lens and diffractive multifocal intraocular lens implantation / 眼科新进展

Objective To compare the vision and visual quality after implantation of refractive rotationally asymmetric mutifocal IOL (SBL-3) and diffractive mutifocal IOL (Zeiss809) in cataract surgery.Methods Totally 80 patients (100 eyes) who underwent cataract surgery in our hospital from May 2016 to June 2017 were chosen in the research,followed by the implantation of SBL-3 in 39 patients (50 eyes,SBL group) and Zeiss809 in other 41 patients (50 eyes,Zeiss group).The gender,age,length of optic axis and corneal curvature between the both groups were not significantly different (all P ＞ 0.05) before surgery.Variables including far,middle and near uncorrected vision acuity,defocus curves,vision quality were observed 3 months after surgery.Objective scattering index (OSI),modulation transfer function cutoff frequency(MTFcutoff) and Strehl ratio (SR) were detected,and objective optical quality analysis system was conducted.Results Both groups has no ocular hypertension and complications after surgery.The far uncorrected vision acuity of both groups in 3 months after surgery showed significant statistic difference from preoperation (both P ＜ 0.01).There has no statistic difference between both groups in far and near uncorrected vision acuity 3 months after surgery (both P ＞0.05).SBL group showed better outcomes than that in Zeiss group in the middle uncorrected vision acuity 3 months after surgery (P =0.04).Defocus curves showed the better middle uncorrected vision acuity in SBL group than that in Zeiss group when the degree was-1.50 D (70 cm).The OSI,MTFcutoff and SR in both groups significantly improved after surgery when compared with before surgery (all P ＜0.05).And the OSI,MTFcutoff and SR 3 months after surgery had no statistic difference between the two groups (all P ＞ 0.05).Questionnaire results showed there were 3 patients in SBL group and 4 in Zeiss group complaining glare at night,and there was no statistic difference between the two groups (P ＞ 0.05).Conclusion Both refractive rotationally asymmetric mutifocal IOL and diffractive multifocal IOL shows satisfactory vision acuity after cataract surgery.Significant improvement of vision quality in both groups can be presented after IOL implantation.

A comparative study of visual quality between implantable collamer lens implantation and femtosecond LASIK for myopia / 中华实验眼科杂志

Background The incidence of myopia is gradually increasing,and how to choose a better corrective method of myopia for the best visual demand is very important.Objective This study was to compare visual quality of implantable collamer lens (ICL) implantation with femtosecond laser in situ keratomileusis (FSLASIK) for moderate and high myopia using double-pass optical quality analysis system (OQAS).Methods A non-randomized controlled clinical trail was performed.Fifty-two eyes with-4.00 to-9.00 D of 26 consecutive patients were included in NO.1 Hospital of Xi'an from January 2015 to January 2016.Twenty-four eyes of 12 patients with the corneal thickness ＜500 μm received ICL implantation as ICL group and 28 eyes of 14 patients which corneal thickness was ≥500 μm underwent FS-LASIK surgery as FS-LASIK group.The demography was matched between the two groups (all at P＞0.05).All the patients were followed-up for 3 months after surgery.The preoperative best corrected distance visual acuity (BCDVA),spherical equivalent (SE),postoperative uncorrected distance visual acuity (UCDVA),BCDVA and SE were examined and compared between two groups.The parameters from OQAS were evaluated and intergrouply compared,including the objective scattering inders (OSI),modulation transfer function (MTF) cut off frequency,Strehl ratio and OQAS values under the contrast of 100％,20％ and 9％ (OV100,OV20,OV9).Results The postoperative BCDVA was not significantly different from preoperative UCDVA in both ICL group and FS-LASIK group (-0.04±t0.10 vs.0.05±0.12;-0.07±0.12 vs.0.00±0.12) (t=3.128,2.358,both at P＞0.05).No statistically significant differnces were found in SE,UCDVA and BCDVA after operation between ICL group and FS-LASIK group (t =1.292,0.900,-0.653,all at P＞0.05).OQAS examination showed that MTF cut off,OSI,Strehl ratio,OV100 were not significantly different after operation between ICL group and FS-LASIK group (t=-2.032,-1.440,-0.224,all at P＞0.05).The postoperative OV20 and OV9 were 0.82±0.14 and 0.80±0.21 in the ICL group,which were significantly higher than those in the FS-LASIK group(0.59±0.15 and 0.47±0.13) (t =4.105,4.702,both at P＜0.05).Conclusions Both ICL implantation and FS-LASIK provide good optical and visual quality for moderate to high myopic eyes,and ICL appears to have a better visual quality in comparison with FS-LASIK under the contrasts of 20％ and 9％.

Effect analysis of cataract surgery with transparent corneal incision in different direction by dual channel vision quality system / 眼科新进展

Objective To investigate the effects of cataract surgery with transparent corneal incision in different directions,and discuss the application of dual channel visual quality analysis system in the evaluation of visual quality before and after cataract surgery.Methods Sixty-four patients (64 eyes) with cataract phacoemulsification combined with intraocuiar lens (IOL) implantation were enrolled in our hospital from January to May in 2016,and randomly divided into 2 groups:Group A with corneal incision in the temporal side of the eyes,group B with upper corneal incision.All the cases were examined with standard logarithmic optical acuity and dual-channel optical quality analysis system.The visual acuity,MTF cutoff,Strehl ratio (SR),objective scattering index (OSI) and contrast ratio were compared between the two groups.The OQAS values were 100％,20％ and 9％.Results (1) The visual acuity and corrected visual acuity of all patients increased gradually from postoperative 1 day to 1 week (P ＜0.05),and the visual acuity gradually stabilized after 1 week.The uncorrected visual acuity and corrected visual acuity at postoperative 1 day and 1 week in group A were significantly higher than those in group B at the same time point(P ＜ 0.05).There was no significant difference in uncorrected visual acuity and corrected visual acuity between the two groups at postoperative 1 month and 3 months (P ＞ 0.05).(2) At postoperative 1 day and 1 week,the OSI values of two groups were higher than those before operation,and all the time points were statistically significant (all P ＜ 0.05).The OSI values of group A at postoperative 1 day(2.81 ±0.89) and 1 week(1.98 ±0.73) were significantly lower than those of group B at 1 day(3.46 ± 1.17) and 1 week(2.61 ± 1.20) (all P ＜ 0.05).There was no significant difference in OSI between postoperative 1 month and 3 months (all P ＞ 0.05).The OV9％ values of the two groups were increased at postoperative 1 day,1 week,1 month and 3 months,and all the time points were statistically significant(all P＜0.05).The value of OV9％ in group A at postoperative 1 day(0.29 ±0.09),1 week(0.33 ±0.12),1 month (0.37 ± 0.14) and 3 months (0.42 ± 0.17) were significantly higher than those in group B at 1 day (0.24 ± 0.10),1 week (0.27 ± 0.09),1 month (0.31 ± 0.09) and 3 months (0.34 ± 0.14),which was statistically significant (all P ＜ 0.05).The MTF,SR,OV100％ and OV20％ values of all the patients were not statistically significant (all P ＞ 0.05).Conclusion In the operation of cataract with the temporal and transparent corneal incision,the postoperative intraocular scattering is small,early visual recovery is fast and the visual quality is high.The long-term effect needs further study.Dual channel visual quality analysis system can further quantify the visual quality parameters,has certain advantage in visual quality assessment.

Clinical Outcome of Small Incision Lenticule Extraction including Visual Quality Analysis

PURPOSE: To present the clinical outcomes of small incision lenticule extraction (SMILE) including visual quality analysis in Korean patients with myopia METHODS: The medical records of 228 eyes of 116 patients who underwent SMILE in HanGil Eye Hospital LASIK Center from May 2014 to Feb 2015 and were followed-up for at least 3 months was analyzed retrospectively. The patients were followed up at 1 day, 1 week, 1 month, and 3 months after the operation. Refractive value, visual acuity, intraocular pressure, and visual quality were measured at each visit RESULTS: Preoperatively, uncorrected distant visual acuity was 0.01 ± 0.02 in log MAR, spherical equivalent was -5.03 ± 1.72 diopters, intraocular pressure was 15.85 ± 2.85 mm Hg, and the objective scattering index (OSI) value was 0.68 ± 0.49. The postoperative uncorrected distant visual acuity was 0.13 ± 0.10, 0.05 ± 0.08, 0.04 ± 0.09, and 0.02 ± 0.04 and OSI was 2.16 ± 1.89, 1.25 ± 0.64, 1.14 ± 0.69, and 0.81 ± 0.36 at 1 day, 1 week, 1 month, and 3 months after the operation, respectively. The postoperative intraocular pressure was 12.55 ± 3.74 mm Hg, 13.03 ± 4.35 mm Hg, 11.65 ± 2.49 mm Hg at 1 week, 1 month, and 3 months after the operation. The efficacy of refractive surgery 3 months after the operation was 0.97 ± 0.11, the safety was 0.99 ± 0.10, and predictability was 99.56% and 100.00% at the range of ±0.5 diopters and ± 1.0 diopter, respectively. CONCLUSIONS: The SMILE operation showed comparable clinical outcomes with conventional refractive surgery in terms of efficacy, safety, and predictability. Intraocular pressure and visual quality normalized gradually throughout the 3-month postoperative period.

Clinical Outcome of Small Incision Lenticule Extraction including Visual Quality Analysis

PURPOSE: To present the clinical outcomes of small incision lenticule extraction (SMILE) including visual quality analysis in Korean patients with myopia METHODS: The medical records of 228 eyes of 116 patients who underwent SMILE in HanGil Eye Hospital LASIK Center from May 2014 to Feb 2015 and were followed-up for at least 3 months was analyzed retrospectively. The patients were followed up at 1 day, 1 week, 1 month, and 3 months after the operation. Refractive value, visual acuity, intraocular pressure, and visual quality were measured at each visit RESULTS: Preoperatively, uncorrected distant visual acuity was 0.01 ± 0.02 in log MAR, spherical equivalent was -5.03 ± 1.72 diopters, intraocular pressure was 15.85 ± 2.85 mm Hg, and the objective scattering index (OSI) value was 0.68 ± 0.49. The postoperative uncorrected distant visual acuity was 0.13 ± 0.10, 0.05 ± 0.08, 0.04 ± 0.09, and 0.02 ± 0.04 and OSI was 2.16 ± 1.89, 1.25 ± 0.64, 1.14 ± 0.69, and 0.81 ± 0.36 at 1 day, 1 week, 1 month, and 3 months after the operation, respectively. The postoperative intraocular pressure was 12.55 ± 3.74 mm Hg, 13.03 ± 4.35 mm Hg, 11.65 ± 2.49 mm Hg at 1 week, 1 month, and 3 months after the operation. The efficacy of refractive surgery 3 months after the operation was 0.97 ± 0.11, the safety was 0.99 ± 0.10, and predictability was 99.56% and 100.00% at the range of ±0.5 diopters and ± 1.0 diopter, respectively. CONCLUSIONS: The SMILE operation showed comparable clinical outcomes with conventional refractive surgery in terms of efficacy, safety, and predictability. Intraocular pressure and visual quality normalized gradually throughout the 3-month postoperative period.

Comparison of Optical Quality Between Two Intraocular Lenses Using Double-Pass Based Optical Quality Analysis System

PURPOSE: To compare postoperative optical qualities between two types of 1-piece aspheric intraocular lenses using the double-pass technique. METHODS: Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and spherical equivalent were evaluated in the subject groups; the first which included 25 eyes implanted with Tecnis(R) ZCB00 and the second which included 16 eyes implanted with Acrysof(R) IQ SN60WF. In addition, modulation transfer function (MTF) cut-off, Strehl ratio, and objective scattering index (OSI) were measured 6 months after cataract surgery in the 2 subject groups using Optical Quality Analysis System (OQAS, Visiometrics S.L., Terrasa, Barcelona, Spain) which is based on the double-pass technique. RESULTS: There were no significant differences in the spherical equivalent, UCVA, BCVA, and OSI between the 2 groups. However, both the MTF cut-off, and Strehl ratio showed statistically significant differences. The MTF cut-off (28.0 +/- 7.79 vs. 20.4 +/- 9.51 c/deg, p = 0.025) and Strehl ratio (0.14 +/- 0.04 vs. 0.12 +/- 0.05, p = 0.042) were higher in the Tecnis(R) ZCB00-implanted group. CONCLUSIONS: The difference in characteristics of intraocular lenses subtly affects the vision quality as measured by values such as MTF cut-off and Strehl ratio after cataract surgery. OQAS based on the double-pass technique is considered useful in more objective estimates of the real retinal image quality after cataract surgery which is difficult to explain simply by measuring visual acuity.

The Recovery of Optical Quality after Laser Vision Correction

PURPOSE: To evaluate the optical quality after laser in situ keratomileusis (LASIK) or serial photorefractive keratectomy (PRK) using a double-pass system and to follow the recovery of optical quality after laser vision correction. METHODS: This study measured the visual acuity, manifest refraction and optical quality before and one day, one week, one month, and three months after laser vision correction. Optical quality parameters including the modulation transfer function, Strehl ratio and intraocular scattering were evaluated with a double-pass system. RESULTS: This study included 51 eyes that underwent LASIK and 57 that underwent PRK. The optical quality three months post-surgery did not differ significantly between these laser vision correction techniques. Furthermore, the preoperative and postoperative optical quality did not differ significantly in either group. Optical quality recovered within one week after LASIK but took between one and three months to recover after PRK. The optical quality of patients in the PRK group seemed to recover slightly more slowly than their uncorrected distance visual acuity. CONCLUSIONS: Optical quality recovers to the preoperative level after laser vision correction, so laser vision correction is efficacious for correcting myopia. The double-pass system is a useful tool for clinical assessment of optical quality.